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Analysis of neural activation in time-dependent membrane capacitance models
Most models of neurons incorporate a capacitor to account for the marked capacitive behavior exhibited by the cell membrane. However, …
Matias Courdurier
,
Leo Medina
,
Esteban Paduro
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The Impact of High-Frequency-Based Stability on the Onset of Action Potentials in Neuron Models
This paper studies the phenomenon of conduction block in model neurons using high-frequency biphasic stimulation (HFBS). The focus is …
Eduardo Cerpa
,
Nathaly Corrales
,
Matias Courdurier
,
Leo Medina
,
Esteban Paduro
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Towards a more accurate quasi-static approximation of the electric potential for neurostimulation with kilohertz-frequency sources*
Objective. Our goal was to determine the conditions for which a more precise calculation of the electric potential than the …
Thomas Caussade
,
Esteban Paduro
,
Matias Courdurier
,
Eduardo Cerpa
,
Warren M. Grill
,
Leo Medina
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A partially averaged system to model neuron responses to interferential current stimulation
The interferential current (IFC) therapy is a noninvasive electrical neurostimulation technique intended to activate deep neurons using …
Eduardo Cerpa
,
Matias Courdurier
,
Esteban Hernández
,
Leo Medina
,
Esteban Paduro
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Multiscale Entropy Analysis of Retinal Signals Reveals Reduced Complexity in a Mouse Model of Alzheimer's Disease
Alzheimer’s disease (AD) is one of the most significant health challenges of our time, affecting a growing number of the elderly …
Joaquín Araya-Arriagada
,
Sebastián Garay
,
Cristóbal Rojas
,
Claudia Duran-Aniotz
,
Adrian Palacios
,
Max Chacón
,
Leo Medina
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Creating a neuroprosthesis for active tactile exploration of textures
Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, …
Joseph E. O'Doherty
,
Solaiman Shokur
,
Leo Medina
,
Mikhail A. Lebedev
,
Miguel A. L. Nicolelis
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DOI
Nerve excitation using an amplitude-modulated signal with kilohertz-frequency carrier and non-zero offset
BACKGROUND Incorporating kilohertz-frequency signals in transcutaneous electrical stimulation has been proposed as a means to overcome …
Leo Medina
,
Warren M. Grill
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Effects of frequency-dependent membrane capacitance on neural excitability
Objective. Models of excitable cells consider the membrane specific capacitance as a ubiquitous and constant parameter. However, …
Bryan Howell
,
Leo Medina
,
Warren M. Grill
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DOI
Volume conductor model of transcutaneous electrical stimulation with kilohertz signals.
OBJECTIVE: Incorporating high-frequency components in transcutaneous electrical stimulation (TES) waveforms may make it possible to …
Leo Medina
,
Warren M. Grill
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DOI
Stochastic Facilitation of Artificial Tactile Sensation in Primates
Artificial sensation via electrical or optical stimulation of brain sensory areas offers a promising treatment for sensory deficits. …
Leo Medina
,
Mikhail A. Lebedev
,
Joseph E. O'Doherty
,
Miguel A. L. Nicolelis
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