Multi-echo acquisition and thermal denoising advances precision functional imaging

Abstract

The characterization of individual functional brain organization with Precision Functional Mapping has provided important insights in recent years in adults. However, little is known about the ontogeny of inter-individual differences in brain functional organization during human development. Precise characterization of systems organization during periods of high plasticity is likely to be essential for discoveries promoting lifelong health. Obtaining precision functional magnetic resonance imaging (fMRI) data during development has unique challenges that highlight the importance of establishing new methods to improve data acquisition, processing, and analysis. Here, we investigate two methods that can facilitate attaining this goal: multi-echo (ME) data acquisition and thermal noise removal with Noise Reduction with Distribution Corrected (NORDIC) principal component analysis. We applied these methods to …

Publication
bioRxiv
Cristian Morales
Cristian Morales
Principal Investigator

Cristian Morales Carrasco is an electrical engineer with an MSc in Electrical Engineering and a PhD in Biomedical Engineering. His research focuses on functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS).